ICP-MS

An overview of ICP-MS

ICP-MS is a multi-element technique for trace analysis where low detection limits (0.0005-1.0 ppb) are required and for high-precision isotope ratio studies. The plasma source is an excellent ion source and most elements from 0-240 amu are ionised into singly charged positive ions (M+ ). Sample preparation is more crucial than in ICP-OES with samples ideally dissolved in 2% HNO3 v/v and with a total dissolved solids content < 0.2 %. Sample volume used is typicaly 1-2 ml depending upon number of isotopes analysed and the type of interference removal required.

The ICP-MS is an Agilent 7500ce with a collision cell and an integrated LC (Agilent 1200 series) system. The collision cell will allow elements that are in the region of the mass spectrum where isobaric interferences are common (e.g 1st row transition elements) to be anaylsed. Helium and Xenon are available as collsion gases and Hydrogen as a reactive gas. The 1200 series LC allows HPLC separated species to be directly aspirated into the ICP-MS and, as the instrument has an organic kit, some organic based buffers can be used.

Access and Charges

Potential GeoScience Users for the ICP-MS should approach Dr Lorna Eades in the first instance to assess whether there is a justifiable need for ICP-MS as opposed to ICP-OES. The instrument is located in room 111b, School of Chemistry (Joseph Black Building, Kings Buildings). Users will be charged on the basis of their time spent on the instrument and must provide an IT form, Purchase Order Number or Cost Center prior to using the instrument.